Research Article

Eco-Friendly Scalp Purifying Serum Made from Zanthoxylum ailanthoides

Chia-Hua Liang 1 *
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1 Department of Cosmetic Science and Institute of Cosmetic Science, Chia Nan University of Pharmacy and Science, Tainan 71710, Taiwan; * Corresponding Author
Applied Functional Materials, 4(3), 2024, 1-6
Published: 30 December 2024
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ABSTRACT

Modern lifestyles impact scalp health as UV radiation, pollution, and stress are increasing. Such factors lead to sensitivity, inflammation, hair loss, and premature graying. To address this, we formulated a plant-based follicle care product to promote scalp and hair health using Zanthoxylum ailanthoides (ZL) extract. Its efficacy was evaluated using cell assays, microbial testing, and stability assessments. HaCaT cells were used for viability and inflammation tests, while B16F10 cells were used for melanin production tests. Stability tests were conducted to measure pH, color, and microbial safety. ZL extracts showed no cytotoxicity, increased melanin production, and reduced inflammation. Therefore, a dual-phase product containing ZL was developed, featuring an upper frozen gel layer and a lower serum layer in the scalp serum formulation. The upper frozen gel helps prevent oxidation, preserves the efficacy of active ingredients, and enhances the moisturizing and reparative effects. The product passed temperature stability tests, long-term storage assessments, and microbial activity as a stable and safe formulation. The scalp serum containing ZL can be used to address scalp issues, enhance overall scalp health and be improved through future innovations in scalp care and treatments.

CITATION (APA)

Liang, C.-H. (2024). Eco-Friendly Scalp Purifying Serum Made from Zanthoxylum ailanthoides. Applied Functional Materials, 4(3), 1-6.

REFERENCES

  1. Luo, J., Ke, J.X., Hou, X.Y., et al. Composition, structure and flavor mechanism of numbing substances in Chinese prickly ash in the genus Zanthoxylum: A review. Food Chemistry 2022, 373, 131454.
  2. Fan, W.L., Wen, C.H., Ma, L.T., et al. Monoterpene synthases contribute to the volatile production in tana (Zanthoxylum ailanthoides) through indigenous cultivation practices. Plant Physiology and Biochemistry 2023, 202, 107969.
  3. Liang, Y.N., Cui, N., Liang, X.B., et al. The complete chloroplast genome sequence of Zanthoxylum ailanthoides Sieb. et Zucc (Rutaceae): an important medicinal plant. Mitochondrial DNA Part B 2024, 9(4), 506–511.
  4. Trüeb, R.M., Henry, J.P., Davis, M.G., Schwartz, J.R. Scalp Condition Impacts Hair Growth and Retention via Oxidative Stress. International Journal of Trichology 2018, 10(6), 262–270.
  5. Duroux, R., Baillif, V., Havas, F., et al. Targeting inflammation and pro-resolving mediators with Anetholea anisita extract to improve scalp condition. International Journal of Cosmetic Science 2022, 44(5), 425–437.
  6. Rattanakaemakorn, P., Suchonwanit, P. Scalp Pruritus: Review of the Pathogenesis, Diagnosis, and Management. BioMed Research International 2019, 1268430.
  7. Trüeb, R.M. Oxidative stress and its impact on skin, scalp and hair. International Journal of Cosmetic Science 2021, 43(5), 463–471.
  8. Nooreen, Z., Tandon, S., Yadav, N.P., et al. Zanthoxylum: A Review of its Traditional Uses, Naturally Occurring Constituents and Pharmacological Properties. Current Organic Chemistry 2019, 23(12), 1307–1341.
  9. Okagu, I.U., Ndefo, J.C., Aham, E.C., Udenigwe, C.C. Zanthoxylum Species: A Review of Traditional Uses, Phytochemistry and Pharmacology in Relation to Cancer. Infectious Diseases and Sickle Cell Anemia. Frontiers in Pharmacology, 12, 713090.
  10. Park, S., & Lee, J. (2021). Modulation of Hair Growth Promoting Effect by Natural Products. Pharmaceutics 2021, 13(12), 2163.
  11. Vaou, N., Stavropoulou, E., Voidarou, C., et al. Interactions between Medical Plant-Derived Bioactive Compounds: Focus on Antimicrobial Combination Effects. Antibiotics 2022, 11(8), 1014.
  12. Ngoc, L.T.N., Moon, J.Y., & Lee, Y.C. Insights into Bioactive Peptides in Cosmetics. Cosmetics 2022, 9(5), 1–22.